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Blood analysis RESULT 33 YO male normal 31 YO male When admitted 12 hours later

ID: 3473194 • Letter: B

Question

Blood analysis

RESULT

33 YO male

normal

31 YO male

When admitted

12 hours later

At time of death

(for reference)

When admitted

12 hours later

At time of death

pH

6.68

6.69

7.11

7.4

6.71

6.71

6.66

pCO2 Torr

61

18

32

40

24

20

55

HCO3 mM

9

2

10

24

3

2.5

12

*CPK

127

298

< 160

1004

4280

10700

MetOH mM

78

62

34

44

34

EtOH mM

33

15

15

* Elevated CPK is indicative of muscle damage/ tissue death

Q3. Why is elevated serum CPK significant?

RESULT

33 YO male

normal

31 YO male

When admitted

12 hours later

At time of death

(for reference)

When admitted

12 hours later

At time of death

pH

6.68

6.69

7.11

7.4

6.71

6.71

6.66

pCO2 Torr

61

18

32

40

24

20

55

HCO3 mM

9

2

10

24

3

2.5

12

*CPK

127

298

< 160

1004

4280

10700

MetOH mM

78

62

34

44

34

EtOH mM

33

15

15

Explanation / Answer

CPK stands for creatine phosphokinase. Its an enzyme that catalyzes creatine into phophocreatine by utilizing a molecule of ATP for each reaction. This is reversible reaction and can regenerate ATP molecules when needed by the body mostly in muscle cells, brain cells and heart cells. It basically serves as an energy reservoir as it utilizes ATP when ATP is abundant and saves the the energy of the phosphate bond in phosphocreatine which is brokendown reversibly to reproduce ATP when ATPs are deficient in body.

An elevated CPK level indicates

heart attack- myocardial infarction.

Excessive muscle break down-rhabdomylysis

Kidney injury, muscle disorder