Sequence 1: 5\'-AUGGACGAAUAGCCUGA-3\' Part A Sequence 1: 5\'-AUGGACGAAUAGCCUGA-3
ID: 301365 • Letter: S
Question
Sequence 1: 5'-AUGGACGAAUAGCCUGA-3'
Part A
Sequence 1: 5'-AUGGACGAAUAGCCUGA-3'
Part B
Sequence 2: 5'-AUGGACGAAUAUGCCUGA-3'
Part C
What type of mutation gave rise to Sequence 2?
Enter your answer as frameshift, nonsense or missense.
Use the codon chart to predict the amino acid sequence produced during translation by the following short hypothetical mRNA sequences.Sequence 1: 5'-AUGGACGAAUAGCCUGA-3'
Sequence 2: 5'-AUGGACGAAUAUGCCUGA-3'Part A
Sequence 1: 5'-AUGGACGAAUAGCCUGA-3'
Sequence 1: 5'-AUGGACGAAUAGCCUGA-3' met-asp-glu-(stop) met-glu-glu-(stop) met-asp-glu-tyr-ala-(stop) met-glu-asp-tyr-(stop)Part B
Sequence 2: 5'-AUGGACGAAUAUGCCUGA-3'
Sequence 2: 5'-AUGGACGAAUAUGCCUGA-3' met-asp-asp-tyr-val-(stop) met-asp-glu-tyr-ala-(stop met-asp-glu-(stop) met-glu-asp-thr-ala-(stop)Part C
What type of mutation gave rise to Sequence 2?
Enter your answer as frameshift, nonsense or missense.
Explanation / Answer
Part A
Sequence 1 - met-asp-glu-stop
Part B
Sequence 2-met-asp-glu-tyr-ala-stop
PartC:-
There is addition of uracil in sequence 1 which results in sequence 2 and it shifts the stop codon,that is why it is a Frameshift mutation.
sequence-1 :-AUG GAC GAA UAG CCUGA
sequence 2:- AUG GAC GAA UAU GCC UGA
(Added uracil is indicated in bold)