Can someone please answer the following questions for me with full explanation p
ID: 3166533 • Letter: C
Question
Can someone please answer the following questions for me with full explanation please Continuation of question Using the representation of a sialic acid derivative bound to the active site of the neuramidase, explain how neuramidase inhibitors such as zanamivir inhibit the hydrolysis of glycoproteins from sialic acid (Figure (a) 09c) and in the treatment of influenza infection. Indicate how the structure of zanamivir differs from the substrate to achieve this. ?? CO2 AcHN NH Asp-151 Glu-227 RNHR Trp-178 Glu-119 Figure Q9(c) (7 marks) 10. Answer ALL parts of this question. (a) List FOUR common problems related to cancer chemotherapy (4 marks) (b) Describe the physicochemical properties of alkylating agents that enable this class of drugs to be effective anticancer drugs. (5 marks) Question 10 continued on page 6Explanation / Answer
10. A) both chemotherapy and radiation to the chest can cause heart problems....like congestive heart failure ,coronary artery disease,arrhythmia. And even hyper tension.
Lung problems are highly common if the person under goes chemotherapy and radiation
Menopause caused by cancer therapy can be worse than natural menopause.
Hormone problems for men if they under go chemotherapy to remove testicles .
Infertility from cancer treatments may last for a short time or they can be permanent.