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Comes in two parts. Bottom continued. Why is a single base-pair deletion mutatio

ID: 318000 • Letter: C

Question

Comes in two parts. Bottom continued.

Why is a single base-pair deletion mutation within a protein-coding sequence more likely to be harmful than a single base-pair change mutation? O Single base-pair deletions change the codon to one that specifies a stop codon. This causes early termination of the polypeptide chain and almost O Single base-pair deletions shift the reading frame and jumble the message at all points after the mutation. A single base-pair change may not even O Single base-pair deletions lead to changing the amino acid in the protein that causes changing of functions of this protein. A single base-pair change Single base pair deletions make amino acid sequence shorter, but a single base-pair change just changes the sequence

Explanation / Answer

Single base-pair deletions shift the reading frame and jumble the message at all points aftr the mutation. A single base-pair change may not even change the amino acid, and if it does, it is possibel the single amino acid change within a protein can be tolerated.