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In a clinical trial of 2150 subjects treated with a certain drug, 24 reported he

ID: 3207509 • Letter: I

Question

In a clinical trial of 2150 subjects treated with a certain drug, 24 reported headaches. In a control group of 1632 subjects given a placebo, 22 reported headaches. Denoting the proportion of headaches in the treatment group by p_c, and denoting the proportion of headaches in the control (placebo) group by p_c. The relative risk is p_t/p_c. The relative risk is a measure of the strength of the effect of the drug treatment. Another such measure is the odds ratio, which is the ratio of the odds in favor of a headache for the treatment group to the odds in favor of a headache for the control (placebo) group, found by evaluating p_t/(1 - p_t)/p_c/(1 - p_c). The relative risk and odds ratios are commonly used in medicine and epidemiological studies. Find the relative risk and odds ratio for the headache data. What do the results suggest about the risk of a headache from the drug treatment? Find the relative risk for the headache data. The relative risk =

Explanation / Answer

Here pt=24/2150=0.011

And pc=22/1632=0.013

Hence relative risk=pt/pc=0.011/0.013=0.85