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In a cell that lacks cytosolic Hsc70: import of proteins into the mitochondrial

ID: 321016 • Letter: I

Question

In a cell that lacks cytosolic Hsc70:

import of proteins into the mitochondrial matrix would be diminished.

proteins in the ER would not fold properly.

the peroxisome would contain more catalase.

generation of ATP from the electron transport chain would happen at the plasma membrane.

a.

import of proteins into the mitochondrial matrix would be diminished.

b.

proteins in the ER would not fold properly.

c.

the peroxisome would contain more catalase.

d.

generation of ATP from the electron transport chain would happen at the plasma membrane.

Explanation / Answer

Answer is option B. Proteins in the ER would not fold properly.

Cytosolic Hsc70 is a chaperone which is a heat shock protein. It helps in translocating protein in the ER and helps in proper folding.