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QUESTION 2 0.0 Based on the information given in the table above, the most likel

ID: 3216560 • Letter: Q

Question

QUESTION 2

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Based on the information given in the table above, the most likely explanation for the differences in rates of ASHD between the initial examination and the yearly follow-up examination in men is:

The prevalence and incidence of ASHD increase with age in men

Case-fatality rates of ASHD are higher at younger ages in men

A classic cohort effect explains these results

The case-fatality rate in ASHD is highest in the first 24 hours following a heart attack

The initial examination measures the prevalence of ASHD, whereas the subsequent examinations primarily measure the incidence of ASHD

Rates of Atherosclerotic Heart Disease (ASHD) per 10,000 Population, By Age and Sex, Framingham, Massachusetts Men Women Age at Beginning of Study ASHD Rates at Initial Exam Yearly Follow-up Exams (Mean Annual Incidence) ASHD Rates at Initial Exam Yearly Follow-up Exams (Mean Annual Incidence) 29-34 76.7 19.4 0.0

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35-44 90.7 40.0 17.2 2.1 45-54 167.6 106.5 111.1 29.4 55-62 505.4 209.1 211.1 117.8

Explanation / Answer

The most likely explanation for the differences in rates of ASHD between the initial examination and the yearly follow-up examination in men is that the initial examination measures the prevalence of ASHD, whereas the subsequent examinations primarily measure the incidence of ASHD.

Hence,

Option E is correct.