QUESTIONS TO ANSWER: 1.Looking at Jane’s lab profile, it is indicative of what c
ID: 322101 • Letter: Q
Question
QUESTIONS TO ANSWER:
1.Looking at Jane’s lab profile, it is indicative of what condition?
2.What are the two most common causes of this condition?
3.Which lab result is critical in the diagnosis of this disease?
4.Discuss the significance of the Hematology results?
Jane L) a 30-year-old woman, was seen in the ER with severe epigastric pain radiating to the back that woke her from sleep. She also complained of nausea and vomiting. The chemistry and hematology tests shown in Tables 2—8 and 2—9 were ordered.
Jane L. Reference Range
Sodi um
140
135-145 mEq/L
Potassium
3.6
3.6—5.0 mEq/L
Chloride
106
98-107 mEq/L
C02
29.0
24.0-34.0 mEq/L
Glucose
116
80-120 mg/dl,
Bilirubin, total
0.2
0.2—1.9 mg/dL
AST
ALP
Protein
26
53
6.8
5-40 IU/L
30-157 IU/L
6.0-8.4 gidL
2120
2121
Reference Range
BUN
13
7—24 mg/dL
Creatinine
1.2
1.2
0.5—1.2 mg/dL
Calcium
9.0
8.8
8.5—10.5 mg/dL
Albumin
4.2
3.5-5.0 g/dL
ALT
23
NT
5—40 IU/L
Amylase
738
265
10-110 IU/L
Lipase
3970*
320
31-186 IU/L
335
NT
13-86 IU/L
Cholesterol
NT
165
Recommended (desirable): < 200 mg/dL
Triglyceride
NT
155
Recommended (desirable): < 250 mg/dL
2120
2121
Reference Range
WBC
RBC
ESR
12.1
4.93
40
10.8
4.76
5-10 x 109/1.
4.0-5.0 x
0—20 mm/h
HDL 35 Recommended (desirable): 60 mg/dL LDL NT 99 Recommended (desirable): 130 mg/dL *Lipemic sample, results rechecked.
Abbreviations: ALT, alanine aminotransferase; ]GT, gamma glutamyltransferase; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NT, not tested.
Table 2-9 " HEMATOLOGY
Abbreviations.' ESR, erythrocyte sedimentation rate; NT, not tested.
Sodi um
140
135-145 mEq/L
Potassium
3.6
3.6—5.0 mEq/L
Chloride
106
98-107 mEq/L
C02
29.0
24.0-34.0 mEq/L
Glucose
116
80-120 mg/dl,
Bilirubin, total
0.2
0.2—1.9 mg/dL
AST
ALP
Protein
26
53
6.8
5-40 IU/L
30-157 IU/L
6.0-8.4 gidL
2120
2121
Reference Range
BUN
13
7—24 mg/dL
Creatinine
1.2
1.2
0.5—1.2 mg/dL
Calcium
9.0
8.8
8.5—10.5 mg/dL
Albumin
4.2
3.5-5.0 g/dL
ALT
23
NT
5—40 IU/L
Amylase
738
265
10-110 IU/L
Lipase
3970*
320
31-186 IU/L
335
NT
13-86 IU/L
Cholesterol
NT
165
Recommended (desirable): < 200 mg/dL
Triglyceride
NT
155
Recommended (desirable): < 250 mg/dL
Explanation / Answer
1. elevated levels of amylase and lipase enzymes indiacate that Jane is suffering from acute pancreatitis.
2. Two most important causes of acute pancreatitis are gallstones ad heavy alcohol use.
3. increase in the level of serum amylase and lipase are indicators of acute pancreatitis Amylase helps in the digestion of starch and lipase causes the brak down of lipids.Pancreas produces both these enzymes ,which are then transported to the small intestine.
4. The hematology tests conducted here include RBC and WBC count .Both the RBC and WBC count lie in the normal range . The RBC count is usually done to determine the presence od diseases like anaemia.Rbc count also provides an estimate of the hemoglobin levels in the blood. WBC levels are indicators of infection in the body. Their levels rise in case of bacterial or viral infections.The erythrocyte sedimentation rate(ESR) determines the rate at which the RBS's settle down to the bottom in a tube.This test has not been conducted over here.