Please answer the question using full explanation of your answer D Question 2 1
ID: 3308222 • Letter: P
Question
Please answer the question using full explanation of your answer D Question 2 1 pts Select one factor which is incorrect about the difficulties in the analysis of enantiomers in GC-MS. a. A minority of detectors can differentiate between enantiomers b. Enantiomers may have a similar fragmentation pattern and this will make it difficult to discriminate between them c. Enantiomers will have a similar boiling point and therefore their retention times may be very similar. d. The analysis of enantiomers is not possible with GC-MSExplanation / Answer
Answer C are incorect
The boiling point of enantiomer are not similar because Physical properties of enantiomer are different. one are R configuration and other are S configuration so their packing arrangement are different, Hence , due to C option factor provide difficulty to analysis of enantiomer in GC-MS.
Derivatisation is always recommended before the injection of enantiomers in GC-MS
The above statement is incorect as in the method no sample derivation is required except for very polar analytes
Because,
a. The minority of detectors can differentiate between enantiomers
b. having same fragmentation pattern
c.
d. a separation of enantiomers is not possible on an achiral column like the Zebron ZB-5MS GC column, only isomers like diastereomers might be separated on an achiral column. Separation of enantiomers requires a chiral GC-column. When you see only one peak for a racemic reference standard on an achiral column this is perfectly normal. Vice versa: when you observe two peaks on an achiral column they cannot be enantiomers - enantiomers have identical physico-chemical properties and must co-elute on such a column