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In Drosophila melanogaster , eyeless ( ey ) is a recessive trait in which the ey

ID: 34025 • Letter: I

Question

In Drosophila melanogaster, eyeless (ey) is a recessive trait in which the eyes are tiny or absent. The ey locus is found on chromosome 4. Monosomy and trisomy for this very small chromosome are compatible with survival and fertility. A trisomic wild-type male with the genotype ey+ ey ey is crossed to an ey+ ey female. Assuming random segregation of chromosomes into gametes, determine the chromosome constitution and phenotypic ratios in the offspring.            

Hint: Refer to Figure 8.21 for a description of chromosome segregation in a trisomic individual, then use the forked-line method/branching diagram to solve the problem.

Explanation / Answer

Cross between parents

ey+ ey ey (male) X ey+ ey (female)

Possible gametes produced by male

ey,

ey,

ey,

ey+

ey+

Possible gamets produced by female

ey+

ey

Offspring produced from this cross

eyey+

eyey,

eyey+

eyey

eyey+

eyey

ey+ey+

ey+ey

ey+ey+

ey+ey

Therefore, ratio of homozygous dominant : Homozygous recessive : heterozygous

= 2 : 5 : 3