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Secure tem 15 Iterm 15 24 hours unfortunancly, AJ has the gcnctic deo de pot cys

ID: 3476908 • Letter: S

Question

Secure tem 15 Iterm 15 24 hours unfortunancly, AJ has the gcnctic deo de pot cystic lddney dsons FKD) which has cussd cnd agc renal clsease for which thc 11 need renal dlalysn te neort ture. Thc emergenc room physician which spadazs in dacase ct the kidncys. MJs parenta an aare ot her knay probiema, bur thay are conused sbaut how this could be related to the bens and Joint pain In herlags, nees and ankks conccmcd that tis lhe rthopedlc resident phvslcan 'imho came to the nergency department introduced hersat to XU and her parents and asked MJ it she had evar had an x-ar w, who had baan var tired to the last ten, days gave the doctor a q1at response. Theresident quickly beg ressing her questor s to MJ 5 parents who respon ed thst MJ had never had sn x-ray, " ' as she usus this 180gusd The old tere scent bout her kidn disesse, trd hat ehe hed veer kin spacialbit n tha n ers haalth are stem Sh had aan thara aboutsic weeks ago when tha racal en tha ba na- that M ould soon need cla yska Her kidna warena kngarttaring m tata aste prodia stam har body 2 adic r sida t physician mad undar and im st immediate MJs parents are rahtl ily ono rna hail ti, nRe har pain but had adt in making tha care fon han een M1% kidna dBARSA and har ading pair td aQA Tr what might be happening to MJ when she heard that she had PKD that had aready caused end-stage renal disease. an Part A Module 6.1 Introduction to Bones as Organs Sreisreierinsa 1. h-bones localed within lendonstat provide teller lerretsge ror "unde movement iunu Short bones uvar when bones such as the ltiu ard fr" r do not unis lo the" "apevted ensath. Part B Modulo 6.2 Microscopic structure of Bon Tissue I ha rthopa 1c rasident a plained that patents lka lu ith chronic kldnev clsease can d velo a bona dsorder calad renal asteatysro ry Hou She xplanad that renal clsaas attacted not only tha tundan ofi te kldnays but also the armour of calcium m MJs oones T e loss o celo um could ed bore per bonu Ted res and possib even bone der mues. The resaden acmited tha : MJ es the irs child tat e had seen with P who rht elso be developing HOO The resident anned to andar sorma lat: tasts and X-rays and dscuss/Al's casa h har attaning n sician berore she was raad 10 m ka ta diagnosis I h would riew MJS X-rays once tha ware ready Osteocytes revert back to osteoblasts in order to scavenge the ittle calcium that i:1vaiable. Osteoclast"il not be able to become asteoctes once they have 5urrounded themselves with extracellular motro. Osteocytes begin to break down the bone etracelular matrix n oder ba man 0stsoolasts cannot perform bona deposition, n which they build up the DOne exraceluar matrix n bloo calcum level5 Part C - Module 6.3 Bone Formation: Ossification for MJ and her develcping banca. The resdent said that ab atirg wauld be mor helpful in the RCD disgnoi the xrays ware prmarily to maka sur J had nat fracbursd anything. Sha continuedo edutate MJ's mam on how banes O lype here to search

Explanation / Answer

Item 15: Part A

Option C: The resident is referring to the tarsals in MJ's ankle

The only short bones in the human skeleton are in the carpals of the wrists and the tarsals of the ankles.

Item 15: Part B

Option D: Osteoblast cannot perform bone deposition, in which they build up the bone extracellular matrix.

Osteoblasts build new bone matrix for which they require calcium.

Part D

Option A: Estrogen has a more potent effect of plate closure than testosterone.

Estrogen causes growth plates to fuse quicker. In men, the same thing happens with testosterone but slower, because testosterone has to be converted to estrogen first.

Part E

Option C: Bone healing may be abnormal because low calcium levels will inhibit osteoblast from forming hard callus

Soft callus to hard callus transformation occurs when osteoblasts travel across the soft callus, transforming into hard bone cells known as osteoclasts.