Place the following events in activation of a B cell by a microbe in the order i
ID: 3482947 • Letter: P
Question
Place the following events in activation of a B cell by a microbe in the order in which they would occur.
Several rounds of division occur, producing many B cells that all express the same B cell receptor.
A B cell differentiates from a lymphocyte stem cell, and the mature B cell expresses a specific type of B cell receptor on its cell membrane.
The B cell's B cell receptor binds to a foreign antigen with high specificity and high affinity.
Second messenger signaling is activated in the B cell.
Gene expression is altered in the B cell, and the B cell begins to divide.
Explanation / Answer
Gene expression is altered in the B cell, and the B cell begins to divide.
Second messenger signalling is activated in the B cell.
The B cell's receptor binds to a foreign antigen with high specificity and high affinity.
A B cell differentiates from a lymphocyte stem cell, and the mature B cell expresses a specific type of B cell receptor on its cell membrane.
Explanation:
B-cells are activated by the binding of antigen to receptors on its cell surface which causes the cell to divide and proliferate. Some stimulated B-cells become plasma cells, which secrete antibodies. Others become long-lived memory B-cells which can be stimulated at a later time to differentiate into plasma cells.