Please solve: Depolarizations (APs) are possible because of the huge amount of s
ID: 3512202 • Letter: P
Question
Please solve:
Depolarizations (APs) are possible because of the huge amount of stored potential energy (in the dCNa: on both sides of the membrane) between Vm and the ENat, set by Gibb-Donnan, which is then released as kinetic energy. Prove mathematically that during the depolarization of the action potential, Vm ENat le., show that the difference between [Na]o and [NaI is relatively small at the peak of the action potential, where the ENat 30 m V and the resting membrane potential (Vm)70 mV. Remember that at this point in the action potential, the influence of K is negligible (5). 7.Explanation / Answer
In resting cell..Na concentration is 135 to 145 milli equivalent and inside the cell is in trace amount and the Na potassium pump maintain this balance.
When there is depolarization of cell Na channels open up and Na due to concentration gradient moves inside cells until positive charge inside cell occur in excess than outside of the cell.
The membrane potential changes by about 100mV during an action potential
Resting potential is -70mv and action potential threshold is 30mv
During resting state Na outside cell was avg 140
During action potential Na is moving inside the cell from outside so the difference between Na out and Na in during action potential decreases