Please explain in detail 3. Fibroblast migration was analyzed on glass slides to

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Please explain in detail

3. Fibroblast migration was analyzed on glass slides to which either fibronectin on collagen was adsorbed. In these experiments, the linear locomotion speed was in the presence of monoclonal antibodies to a2 integrin under serum-free culture determined a) ? 40 20 10 10 10t10 ECM Protein] (molecules/ym') The results of a typical experiment are shown above. One curve represents fibroblast migration on a fibronectin-coated slide and the other represents fibroblast migration on a collagen-coated slide, both in the presence of antibodies to a2 integrin (dotted or solid line) likely represents the results for a fibroblast grown on a fibronectin coated slide in the presence of antibodies to a2 integrin? Explain. . Which curve

Explanation / Answer

Answer -

Dotted line represents fibronectin coated slide.

Explanation - The dotted line represents the fibronectin coated slide. As fibronectin provides growth to fibroblasts, so more the growth more the locomotion.

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