Choose the following to answer: Topoisomerase, helicase, telomerase, primase, en
ID: 37074 • Letter: C
Question
Choose the following to answer: Topoisomerase, helicase, telomerase, primase, endonuclease, 5' to 3' exonuclease, SSB, sliding clamp, 3' to 5' exonuclease, "MUT" system in E. Coli, Okazaki fragments, DNA ligase, abasic site, thymine dimers, glycosylase, double strand breaks, AP endonuclease, DNA mismatches, clamp loader, DNA polymerase, uracil glycosylase, endonuclease, uracil in DNA.
1. Coats the single-stranded regions adjacent to the replication fork
2. Synthesizes the first few nulcoetides of Okazaki fragments
3. Repairs DNA mismatches AFTER passage of the replication fork
4. Can cut phosphodiester bonds (multiple answers). I have topoisomerase and AP endonuclease so far.
5. Used for removal of primers and also for "repair" synthesis of DNA: DNA polymerase?
6. Cuts the DNA on either site of a thymine dimer
7. Short pieces of DNA that have RNA at their 5' ends
8. DNA polymerases that "clean up" after lagging strand synthesis must have this activity
9. Replicates the ends of eukaryotic chromosomes
10. Is removed by uracil glycosylase
11. "Coats" the single strands of DNA after the helix is unwound at the replication fork.
12. Cuts one strand of DNA as part of several types of DNA repair
Explanation / Answer
1. Coats the single-stranded regions adjacent to the replication fork: SSB
2. Synthesizes the first few nulcoetides of Okazaki fragments: primase
3. Repairs DNA mismatches AFTER passage of the replication fork: "MUT" system in E. Coli
4. Can cut phosphodiester bonds: endonuclease, AP endonuclease
5. Used for removal of primers and also for "repair" synthesis of DNA: DNA polymerase
6. Cuts the DNA on either site of a thymine dimer: AP endonuclease
7. Short pieces of DNA that have RNA at their 5' ends: primase
8. DNA polymerases that "clean up" after lagging strand synthesis must have this activity: 5' to 3' exonuclease
9. Replicates the ends of eukaryotic chromosomes: telomerase
10. Is removed by uracil glycosylase: uracil in DNA.
11. "Coats" the single strands of DNA after the helix is unwound at the replication fork: SSB