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Please give me information about it , thanks 1.Discuss what is angiogenesis and

ID: 40707 • Letter: P

Question

Please give me information about it , thanks

1.Discuss what is angiogenesis and why you can target this process to stop cancer growth. Summarize the targets and the effects of the various therapeutic agents against cancer that are currently approved or undergoing late clinical trials.

2.Discuss how you can use the common bacterial vaccine BCG can be used this to fight certain type of cancer. Discuss ways that you can improve the effectiveness of this treatment

3.Discuss the various strategies for developing cancer vaccines. Name some examples of cancer vaccines and how they can help the patients fight cancer.  

Explanation / Answer

Answer:

1)

Angiogenesis is the formation of new blood vessels. This process involves the migration, growth, and differentiation of endothelial cells, which line the inside wall of blood vessels.

The process of angiogenesis is controlled by chemical signals in the body. These signals can stimulate both the repair of damaged blood vessels and the formation of new blood vessels. Other chemical signals, called angiogenesis inhibitors, interfere with blood vessel formation. Normally, the stimulating and inhibiting effects of these chemical signals are balanced so that blood vessels form only when and where they are needed.

Angiogenesis plays a critical role in the growth and spread of cancer. A blood supply is necessary for tumors to grow beyond a few millimeters in size. Tumors can cause this blood supply to form by giving off chemical signals that stimulate angiogenesis. Tumors can also stimulate nearby normal cells to produce angiogenesis signaling molecules. The resulting new blood vessels