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Assume that you are working with Drosophila and are studying genes, a, b, c, d,

ID: 43152 • Letter: A

Question

Assume that you are working with Drosophila and are studying genes, a, b, c, d, e, and f that are all linked in a region on a chromosome, but their order is unknown. In your work, you find that five deletions in the same region uncover recessive alleles of the genes as follows:

Deletion 1 uncovers a, b, and c.

Deletion 2 uncovers a and c.

Deletion 3 uncovers a, c, and e.  

Deletion 4 uncovers c, d, and e.

Deletion 5 uncovers d, e, and f

a. What is the order of the genes?

b. Suppose you systematically attempt to generate a chromosomal deletion (using X?rays) that lacks all six genes, but you are unsuccessful. Suggest a plausible explanation for this.

Explanation / Answer

a. order of genes is

f d e c a b

b. since all 6 genes are deleted it will cause probably a light band and thus a higher conc. of the sample can be tried to test the results.

or else i may sound unreasonable but I think due to lack of all genes the entire chromosome is deleted so no results seen.