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Indicate true (T) and false (F) statements below regarding the interaction of ce

ID: 43784 • Letter: I

Question

Indicate true (T) and false (F) statements below regarding the interaction of cells with the extracellular matrix using matrix receptors. Your answer would be a four-letter string composed of letters T and F only, e.g. TFTT.
( ) Integrins are the only known matrix receptors in animal cells.
( ) Integrins can transmit signals in both directions across the membrane; that is, both outside-in and inside-out.
( ) Tension can increase the binding affinity of an integrin for its intracellular and extracellular ligands.
( ) Integrins can convert molecular signals into mechanical ones.

Explanation / Answer

(F) Integrins are the only known matrix receptors in animal cells.

(T) Integrins can transmit signals in both directions across the membrane; that is, both outside-in and inside-out.

(T) Tension can increase the binding affinity of an integrin for its intracellular and extracellular ligands.

(T) Integrins can convert molecular signals into mechanical ones.