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College-level Genetics: Transcription regulation 1. Transcriptional regulation i

ID: 48429 • Letter: C

Question

College-level Genetics: Transcription regulation

1. Transcriptional regulation in eukaryotes is controlled by both cis- and trans-acting s The following strctue elements. The following structure was isolated from honey bees. It shows such elements as well as parts of a gene body indicated with relative positions. The arrow denotes the transcription start site (the drawing is not in scale). 5' 3 3' Figure 1 A) Indicate what the elements or segments, number 1, 2, 3 and 4, are most likely to 5 30 stand for B) Which numbered segments can interact with trans-acting factors? C) Which numbered segments are cis-acting elements?

Explanation / Answer

A)

1 stands for a coding sequence or exon.

2 stands for RNA polymerase.

3 stands for the promoter.

4 stands for an inducer.

B)

The segments 3 and 4 interact with trans- acting elements because these segments are located upstream and are indicated with '-' sign.

C)

The segment 1 is a cis - acting element and contains +1 sign.