Replication of DNA requires a primer to initiate DNA synthesisbecause A. DNA pol

Question

Replication of DNA requires a primer to initiate DNA synthesisbecause A. DNA polymerase can polymerize nucleotides only in the 5 to3 direction B. DNA polymerase has a 3 to 5 exonuclease activity C. DNA polymerase can add a nucleotide only to a base pairednucleotide with a free 3 end D. DNA polymerase can add its first nucleotide only to an RNAchain E. DNA polymerase can polymerize DNA only in shortfragments Replication of DNA requires a primer to initiate DNA synthesisbecause A. DNA polymerase can polymerize nucleotides only in the 5 to3 direction B. DNA polymerase has a 3 to 5 exonuclease activity C. DNA polymerase can add a nucleotide only to a base pairednucleotide with a free 3 end D. DNA polymerase can add its first nucleotide only to an RNAchain E. DNA polymerase can polymerize DNA only in shortfragments

Explanation / Answer

Replication of DNA requires a primer to initiate DNA synthesisbecause C. DNA polymerase can add a nucleotide only to a base pairednucleotide with a free 3 end DNA polymerase needs a free 3'-OH group to extend the strand.Like RNA polymerase it cannot synthesise from scratch but needs aprimer. hope it helps
C. DNA polymerase can add a nucleotide only to a base pairednucleotide with a free 3 end DNA polymerase needs a free 3'-OH group to extend the strand.Like RNA polymerase it cannot synthesise from scratch but needs aprimer. hope it helps

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