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Replication is a multiple-steps process that involves many different enzymes. Fo

ID: 226605 • Letter: R

Question

Replication is a multiple-steps process that involves many different enzymes. For each of the following replication step (A-to-I), indicate the enzyme that mediates the process (1 point each). Then, order the steps (from 1 to 9) as they chronologically occur (and as you have been taught in the class) (4 points).

A. Small DNA fragments of ~200bp are synthesized Enzyme: ________________________________________ Order: ___________

B. The DNA helix is further unzipped Enzyme: ________________________________________ Order: ___________

C. A short RNA fragment is synthesized to serve as a primer for the replication of the lagging strand template Enzyme: __________________________________ Order: ___________

D. RNA is replaced with DNA Enzyme: ________________________________________ Order: ___________

E. A short RNA fragment is synthesized to serve as a primer for the replication of the leading strand template Enzyme: ________________________________________ Order: ___________

F. Double Strand DNA is denatured at the origin of replication Enzyme: ________________________________________ Order: ___________

G. DNA fragments are joined together Enzyme: ________________________________________ Order: ___________

H. The leading strand is synthesized Enzyme: ________________________________________ Order: ___________

I. RNA fragments are degraded Enzyme: ________________________________________ Order: _

Explanation / Answer

A. DNA polymerase III

B.Helicase.

C. Primase.

D. DNA polymerase I.

E. Primase.

F. Initiator protiens.

G. Ligase.

H. DNA polymerase III.

I RNAse or DNA polymerase I.

Chronological order;

F, B. E C D A H I G