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Carboxylic acids and their derivatives can be reduced using NaBH_4 followed by a

ID: 522743 • Letter: C

Question

Carboxylic acids and their derivatives can be reduced using NaBH_4 followed by an aqueous acid workup. The product of an aldol addition reaction can be dehydrated to form an alpha, beta-unsaturated carbonyl compound. The electrophile in the nitration of benzene is the nitrate anion. A benzene ring with an -OH bonded to it is referred to as "phenyl." Nucleophiles react with aldehydes and ketones to form tetrahedral carbonyl addition intermediates. A Grignard reagent cannot be formed in the presence of an NH, OH, or 5H group. Aldehydes can be oxidized to ketones and carboxylic acids. Friedel-Crafts alkylation is not subject to rearrangement. A carboxylic acid is reduced to a 1 degree alcohol by H_2/Pt. The C-C double bonds in benzene do not undergo the same addition reactions that the C-C double bonds in alkenes undergo. An amino group can be directly added to a benzene ring via an electrophilic aromatic substitution reaction. An amine with an -NH_2 group bonded to a tertiary carbon is classified as a tertiary amine. In a compound that contains both an aldehyde and a C-C double bond, each functional group can be reduced exclusive of the other. Aldehydes react with Grignard reagents (followed by acid workup) to form 1degree alcohols. An intramolecular aldol reaction favors five- and six-membered rings over four-, seven-, and eight- membered rings. A carbonyl group is polarized such that the oxygen atom is partially positive and the carbon atom is partially negative. A carboxylic acid that has been deprotonated is called a carboxylate. An ester can be converted to an acid halide in one step. An ester of formic acid reacts with Grignard reagents to form a 3degree alcohol. The reactivity of a carboxylic acid derivative is dependent on the stability of its leaving group.

Explanation / Answer

True/False statement,

1. False

2. True

3. False

4. False

5. True

6. True

7. False

8. False

9. False

10. True

11. False

12. False

13. True

14. False

15. True

16. True

17. True

18. True

19. False

20. False