Classify each of the given structures as being an ester, acyl chloride, acid anh
ID: 529217 • Letter: C
Question
Classify each of the given structures as being an ester, acyl chloride, acid anhydride or amide. How are reactions between aldehydes and nucleophiles fundamentally different than reactions between acyl chlorides and nucleophiles? (Only one answer is correct.) (a) Aldehydes do not form tetrahedral intermediates with nucleophiles. (b) Acyl chlorides readily form enol tautomers. (c) Aldehydes are readily oxidized by nucleophiles to carboxylic acids. (d) Acyl chlorides have a leaving group, cl^- whereas aldehydes do not. Rank the following carboxylic acid derivatives in decreasing order of reactivity (most reactive least number): (a) amide (b) ester (c) chloride (d) acid anhydride What are the products?Explanation / Answer
14. general formula of...
ester ( - COOR) : option D
acyl chloride ( -COCl): option C
acid anhydride ( -RCO-O-COR): option A
amide ( -CONHR) : option B
15. option D will be right answer
both aldehyde and acid chloride will formed tetrahedral intermediate of enol form when the nucleophile attacks the carbon of carbonyl group (-C=O). in the second step Cl- will remove from acyl chloride compound to give carbonyl compound whereas in case of aldehyde compound there is no leaving group.
16. better the leaving group higher will be reactivity. based on this more reactive to least reactive will be..
C > D > B > A