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Blouhemistry Exam 2 Fall 2009 1. DNA is thermodynamically unstable in aqueous so

ID: 529738 • Letter: B

Question

Blouhemistry Exam 2 Fall 2009 1. DNA is thermodynamically unstable in aqueous solution a. b. False 2. The acidic pKa around 3 for a nucleic base such as a purine is best assigned to which of the following groups? a. NH-) (-NH-) C. OH d. N-) NH2 3. The form of DNA most commonly found in chromosomes is a. Z-DNA b. Circular DNA. c. Linear single-stranded DNA d. Linear double-stranded DNA 4. The genome of bacteria is in almost all cases a. A circular double-stranded DNA b. Linear single-stranded DNA c. Circular single-stranded DNA d. Double-stranded RNA e. None of the above 5. A solution containing 100mMadenosine plus 100mM thymidine mononucleotides would be expected to have the same absorbance value measured at 260nm as a solution containing 1mM poly-dA plus 1mM poly-dT each chain being 100 bp in length. a. True b. False helix like NOTE: Poly-dA and poly-dT chains combine to form a double 6. normal DNA mechanism of Pyrophosphate may be considered a leaving group" in the DNA synthesis by DNA polymerases. a. True 7. b. False stranded oligonucleotide can Which of the following sequences of a single form a hairpin structure containing at least four Watson-Crick base pairs in a row? a. AATT GCTTGCAATCC. b. TTGCATGCAATT CCG c. ACATCG ATATCGAT d. TATACGATAGCG e. None method relies on the use of 8. DNA sequencing by the Sanger

Explanation / Answer

Ans 1 b false

DNA is the gentic material which is present in the nucleus of human cell.

DNA is stable in aqueous solution as it has hydrogen Bonds between the bases , hydrogen bonds between the bases and the surrounding molecules and the base stacking interactions between the adjacent bases.