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In E coli a region of a gene with repeats of the sequence CTGG will be prone to

ID: 54324 • Letter: I

Question

In E coli a region of a gene with repeats of the sequence CTGG will be prone to reversion. missense mutation. nonsense mutation. frameshift mutation. amber mutation. Fragile X syndrome is caused by trinucleotide repeats. free radicals. microdeletions 5-Bromouracil. depurination. During mutagenic treatment with nitrous acid, an adenine deaminates to form hypoxanthine. which bonds like guanine. The mutational event would be AT to CG AT to GC AT to TA GC to AT GC to IA In E coli, mutation arising during repair is mostly by thymine dimer splitting. excision repair. mismatch repair. recombinational repair. SOS repair. Trinucleotide repeat disorders are the result of a high rate of mutation throughout the genome. extensive duplication of a single codon. deviations from the genetic code in human mitochondria. tRNAs failing to recognize specific codons. transversions of the DNA bases in a coding sequence. If an incorrect base is incorporated during DNA synthesis and is not corrected by DNA polymerase, it can be corrected by postrcplication repair. This involves detection of the mismatch. a recognition of the methylation status of the DNA strands. a process similar to excision repair. All the above. None of the above.

Explanation / Answer

2. D (frame shift)

4 A    (trinucleotide repeats)

5. B (AT to GC)

6 E   (sos repair)

8. B (extensive duplication of a single codon.)

9. D   (All the above)