Map ota rate cat rate ncat From the rates given below, calculate the rate enhanc
ID: 55508 • Letter: M
Question
Map ota rate cat rate ncat From the rates given below, calculate the rate enhancement and the MA't in kJ/mol at T= 25 Uncatalyzed rate 10-s1 Catalyzed rate 102 s-1 Number Rate enhancement-11 × 108 Number Scroll down to complete this question MG45.6 45.6kJmol Enter as a whole number. Suppose that a mutation of the above enzyme decreases the catalytic rate by 4 orders of magnitude. The decreased rate indicates that the mutation has caused AGo to increase. By how many kJ/mol has the activation energy increased in the mutant enzyme compared to the wild-type (unmutated) enzyme? Number 44.9 kJ/mol Enter as a whole number.Explanation / Answer
The activation energy is 21.3 kj/mol if catalyzed rate is decreased by 4 magnitudes
Consider the rate decreased by 4 magnitudes in the uncatalyzed rate. Then, activation energy required is:
The activation energy required is 63.8 kj/mol. 18 kj/mol of extra activation energy is required.