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I know you need a data set to answer these question, which is not included here.

ID: 604773 • Letter: I

Question

I know you need a data set to answer these question, which is not included here.But can you give me an overall answer to how to approach this question. You could use similar compounds to show me how to solve it.


overall outline of the reaction:

benzaldehyde => benzoin => 1,2-diphenyl-1,2-ethanediol => 1,2-diphenyl-1,2-ethanediol + 2,2-dimethoxypropane => 2,2-dimethyl-4,5-diphenyl-[1,3]dioxolane.


1) Use the H NMR spectrum of the purified cyclic acetal to identify the major diastereomer From borohydride reduction. There are no minor diastereomers. Draw its structure including stereochemistry. Determine the ratio between major:minor.


2) Explain the stereoselectivity from the crude H NMR of the cyclic acetal.

Explanation / Answer

read the following doc https://docs.google.com/open?id=1g--cadSYdy_5iwb_xVo4gamrYwN0mBPJYE4UsbBaludjBWTZB-3ahKUdzX8G