I need hep answering 2-5 1. Name two specific chemokines and the cells that resp
ID: 60730 • Letter: I
Question
I need hep answering 2-5
1. Name two specific chemokines and the cells that respond to them.
CCL13 is a homeostatic chemokine and monocytes/macrophages and eosinophils respond to them.
CCL2 is an inflammatory chemokine and T-lymphocytes, monocytes/macrophages and mast cells respond to them.
2.) Pick one of your choices in 1.) and describe the signaling pathway, beginning with the chemokine and its receptor and ending with the cytoskeleton, that connects the chemokine with cellular movement.
#3 The contractile ring is the structure that forms the cleavage furrow during cytokinesis of animal cells.
4.) What is the contractile ring made of?
5.) How does the contractile ring get positioned correctly during mitosis? (I.e., what cellular structures or molecules guide the formation of the contractile ring?)
6.) Describe the actions of Rho, ROCK, actin, and myosin-2 at the contractile ring and how the cell regulates cytokinesis through these proteins.
Explanation / Answer
4. Contractile ring is made up of microfilaments and actin filaments. These two filaments are concentrated at the cleavage region of the cell. Cleavage is driven by actin and myosin motor proteins, which are the same proteins involved with muscle contraction. During cytokinesis, the contractile ring tightens around the cytoplasm of the cell until the cell membrane is pinched off into two daughter cells.