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Consider this couple in Answering question either of the two questions below.: t

ID: 60991 • Letter: C

Question

Consider this couple in Answering question either of the two questions below.: the husband is homozygous dominant with respect to blood type antigens, his genotype is AA+ . The wife has type “O-“. .


6-   What is the epitope that determines the blood group A and B? Will this couple experience a situation where their children will suffer from erythroblastois fetalisor or erythroblastosis neonatorum?


7-   If one of their children has to receive multiple blood transfusios, which parent is the best donor? Explain your answer.

Explanation / Answer

RBC bears O- type transmembrane glyco-pretein over their cell- emebrane if the end carbohydrate residue of O- antigen contain N- acetyl glucosamine then such RBCs belong to A- type bloood group while when galactose acts as end carbohydrate residue on O- antigen such RBCs belong to B- type bloood group.

It also possible that both kind of transmembrane glyco-pretein i.e. A- and B- type present over the RBC of an individual then their group is AB- type.

It also possible that neither kind of transmembrane glyco-pretein i.e. A- and B- type present over the RBC of an individual then their group is O- type.

+/- in blood grouping represent presence and absence of Rhesus factor (a kind of transmembrane glyco-pretein) over RBCs cell surface.

Yes this couple baby suffers from erythroblastois fetalisor or erythroblastosis neonatorum.

baby will have same blood gruop with his/ her father so father is best donor for her baby