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The Na +-glucose sym port system of intestinal epithelial cells couples the \"do

ID: 633567 • Letter: T

Question

The Na +-glucose sym port system of intestinal epithelial cells couples the "downhill" transport of two Na + ions into the cell to the "uphill" transport of glucose, pumping glucose into the cell against its concentration gradient. If the Na + concentration outside the cell ([Na+]out) is 153 mM and that inside the cell ([Na+]in) is 19.0 mM, and the cell potential is -49.0 mV (inside negative), calculate the maximum ratio of [glucose]in to [glucose]out that could theoretically be produced if the energy coupling were 100% efficient. Assume the temperature is 37 degree C.

Explanation / Answer

let the ratio be x.so,

49*10^-3=0.059*log(153/(19*x))

or x=1.18968