Please answer and explain the following: 4. Consider the apical location of a pa

Question

Please answer and explain the following:

4. Consider the apical location of a particular protein expressed in epithelial cells, illustrated in Figure A below. When a molecule that chelates calcium is added to the cell culture medium, you observe a redistribution of that protein around the entire cell, shown in Figure B. Which is most likely to be true about the role of calcium in maintaining an apical distribution of protein A? (a) calcium is required to maintain the structural integrity of the junctional complex (b) calcium is required for the binding of the junctional proteins to the cell cortex (c) calcium is a structural component of protein A (d) calcium inhibits intracellular transport of protein A

Explanation / Answer

The most probable reason is (a) Calcium is required to maintain the structural integrity of the junctional complex.

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