Please answer and explain the following: 4. You have generated antibodies that r

Question

Please answer and explain the following:

4. You have generated antibodies that recognize the extracellular domain of the Ca2^+ -pump. Adding these antibodies to animal cells blocks the active transport of Ca^2+ from the cytosol into the extracellular environment. What do you expect to observe with respect to intracellular Ca^2+? (a) Ca^2+ -pumps in vesicle membranes keep cytosolic calcium levels low. (b) Ca^2+ -pumps in the endoplasmic reticulum membrane keep cytosolic calcium levels low. (c) Ca^2+ -pumps in the Golgi apparatus keep cytosolic calcium levels low. (d) Ca^2+ concentrations in the cytosol increase at a steady rate.

Explanation / Answer

The correct option is (c) Ca2+-pumps in the Golgi apparatus keep cytosolic calcium levels low.

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