An anticodon on a tRNA has the sequence 5\'–GCA–3\'. What would be the effect on
ID: 71320 • Letter: A
Question
An anticodon on a tRNA has the sequence 5'–GCA–3'. What would be the effect on translation if the G in the anticodon were mutated to a U?
A) The anticodon could pair to the serine codon 5'–UCA–3', and a cysteine would be incorporated at all points where a serine should have been incorporated.
B) The anticodon could pair to the threonine codon 5'–ACU–3', and a threonine would be incorporated at all points where a cysteine should have been incorporated.
C) The anticodon could pair to the serine codon 5'–AGU–3', and a serine would be incorporated at all points where a cysteine should have been incorporated.
D) The anticodon could pair to the stop codon 5'–UGA–3', and instead of stopping translation, a cysteine would be incorporated and translation could continue.
Explanation / Answer
So, given anticodon is 5'- GCA-3'; codon will be 5'- CGU-3'. This is the codon for arginine.
If G in anticodon is mutated to U, then the anticodon becomes 5'-UCA-3'; then codon will be 5'-AGU-3'; This codes for serine.
Therefore, C is the correct answer.