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Assume that defects in a hypothetical gene X have been linked to antisocial beha

ID: 72619 • Letter: A

Question

Assume that defects in a hypothetical gene X have been linked to antisocial behavior. Two copies of a defective gene X predispose a child to bad behavior from childhood, whereas a single copy of the gene seems to produce no symptoms until adulthood. Because early treatment can counteract the effects of the gene, a program of voluntary genetic testing is being performed with delinquent prospective parents. Charles S. and Caril Ann F. have been arrested on charges of robbery and assault, and Caril Ann is pregnant with Charles’s child. You obtain DNA samples from Charles, Caril Ann, and the fetus. You digest these samples with NotI and use these samples to perform two Southern blots, which you probe with two different oligonucleotide probes, A and B, that hybridize to different parts of the normal gene X, as shown in the figure below.

Based on the data from the Southern Blot shown above, _______ individual(s) have defects in gene X. The parents have ______ defective copy(ies) of the gene, and the fetus has ______ defective copy(ies).

Potential words

one, two, three

Explanation / Answer

Three individual(s) have defects in gene X. The parents have __one____ defective copy(ies) of the gene, and the fetus has __two____ defective copy(ies).