Materials traffic through the endomembrane system of eukaryotic cells via vesicl
ID: 78374 • Letter: M
Question
Materials traffic through the endomembrane system of eukaryotic cells via vesicles. There are two coat proteins COP I and COP II that assemble vesicles for transport along microtubules. COP I coated vesicles undergo retrograde transport, for example, to move materials from the Golgi back to the ER. COP II coated vesicles undergo anterograde transport to move materials from the ER outward.
(1 pt) Which motor protein (myosin, kinesin or dynein) interacts with COP I vesicles? ______________
(1 pt) Which motor protein interacts with COP II vesicles? ______________
(1 pt) Some proteins that traffic in this system contain a KDEL amino acid signal sequence for retention in the ER that interacts with a KDEL receptor protein. Would you expect the KDEL receptor protein to be found associated with COP I or COP II coated vesicles? _________
Explanation / Answer
The golgi complex is a network of stacked membranes known as cisternae centered around the microtubule. The term COp refers to coat protein complex. COP 1 consists of seven subunits which form the protein complex which is heptameric.
The motor protein t
The motor protein that interacts with COP I vescicles is Myosin.
The motor protein that interacts with COP II vescicles is Kinesin.
COP I coat proteins have complex functions in maintaining the normal structure of mammalian interphase by intra -golgi trafficking.
Therefore, KDEL receptor protein to be found associated with COP I coated vesicles.