Need help with Cell Bio please. It is very important to my final grade. Thank yo
ID: 80332 • Letter: N
Question
Need help with Cell Bio please. It is very important to my final grade. Thank you in advance.
Below are a series of false statement regarding the properties of cancer cells. Under each, explain why they are false.
1. Tumor cells invade and colonize territories that normally belong to other cells. ________________________________________________________________________
2. Unlike in normal tissues, cell death is extremely rare in tumors. ________________________________________________________________________
3. Tumor cells grow and proliferate in defiance of normal restraints. ________________________________________________________________________
4. Malignant tumors are composed of cells that grow and proliferate, but still have not acquired invasiveness. ________________________________________________________________________
5. A single mutation is enough to turn a normal cell into a cancer cell. ________________________________________________________________________
Explain how stem cells know which cell will remain a stem cell and which will begin differentiation. Include any/all described methods from the book/PPTs/internet. ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________
In medical oncology, PET (positron emission tomography) is used to selectively image tumors in the body and to monitor cancer progression and response to treatment. Before performing a PET scan, the patient should fast for at least several hours for blood glucose to be sufficiently low. At the time of the scan, the positron-emitting glucose analog fluorodeoxyglucose (FDG) is injected into the bloodstream and the patient is asked to wait for up to an hour while avoiding physical activity. Finally, the scanner moves slowly over the body to reveal the location of possible tumors. Why do you think the patient should avoid physical activity before the scan? ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________
Define:
Totipotent: ______________________________________________________________
Pluripotent: ______________________________________________________________
Multipotent: _____________________________________________________________
Unipotent: ______________________________________________________________
Tumor-Supressor Gene: ____________________________________________________
Proto-oncogene: __________________________________________________________
What genes have you already discovered aid in maintaining pluripotency? (Hint: iPS) ___________________________________________________________________________
What is a hematopoietic cell, and how does it differ from stem cells? ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________
A researcher is studying limb regeneration in the newt Notophthalmus viridescens. She transplants skeletal muscle cells from a transgenic newt that expresses green fluorescent protein (GFP) in all of its cells into the limb of a wild-type recipient newt. She then amputates the recipient limb right at the site of the graft, such that the stump contains GFPexpressing cells. She repeats this experiment several times, finding that GFP is only detected in the muscle cells. Why would this be?
_________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
Explanation / Answer
statement 1,2,3 and 5 are correct and four is incorrect because a tumor is considered as a Cancer if it is malignant means when its cells acquired the ability to invade surrounding tissues