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There are three RNA polymerases in eukaryotic cells, designated I, II, and III.

ID: 808483 • Letter: T

Question

There are three RNA polymerases in eukaryotic cells, designated I, II, and III. They differ in their functions, and they can be distiguished experimentally by their sensitivity to alpha-amanitin, a poison from the mushroom Amanita phalloides. Match each polymerase to its function and aplha-amanitin sensitivity. Function: Synthesizes mRNA. Synthesizes pre-ribosomal RNA. Synthesizes tRNA and small RNA?s. RNA Polymerase I Inhibition by alpha-amanitin: RNA Polymerase II RNA Polymerase Ill Not inhibited. Inhibited by high concentrations. Inhibited by low concentrations.

Explanation / Answer

Function:

RNA Polymerase 2 Synthesizes mRNA

RNA Polymerase 1 synthesizes pre-ribosomal RNA

RNA Polymerase 3 synthesizes tRNA and other small RNAs.

Inhibition:

RNA Polymerase 1 is not inhibited

RNA Polymerase 3 is inhibited by high concentrations

RNA Polymerase 2 is inhibited by low concentrations