There are three RNA polymerases in eukaryotic cells, designated I,II, and III. T

Question

There are three RNA polymerases in eukaryotic cells, designated I,II, and III. They differ in their functions, and they can be distiguished experimentally by their sensitivity to alpha-amanitin, a poison from the mushroom Amanita phalloides. Match each polymerase to its function and alpha-amanitin sensitivity. Function Synthesizes mRNA. Synthesizes pre-ribosomal RNA, Synthesizes tRNA and small RNA?s RNA Polymerase I RNA Polymerase II RNA Polymerase III Inhibition by alpha-amanitin: Not inhibited Inhibited by high concentrations. Inhibited by low concentrations.

Explanation / Answer

Function:

RNA Polymerase 2 Synthesizes mRNA

RNA Polymerase 1 synthesizes pre-ribosomal RNA

RNA Polymerase 3 synthesizes tRNA and other small RNAs.

Inhibition:

RNA Polymerase 1 is not inhibited

RNA Polymerase 3 is inhibited by high concentrations

RNA Polymerase 2 is inhibited by low concentrations

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