The diagram below shows a DNA replication bubble in a salmon cell. The circles i
ID: 81094 • Letter: T
Question
The diagram below shows a DNA replication bubble in a salmon cell. The circles indicate the origin of replication. The four letters (A, B, C, D) show where new DNA strands are being synthesized. a. For each of the four letters, indicate whether the DNA being made there is a leading strand or a lagging strand. b. Draw one leading strand on the diagram, indicating the RNA primer, 5' and 3" ends c. If you add a chemical that inhibits the enzyme DNA ligase, which strand(s) (A, B, C, D) would be most affected? Why?Explanation / Answer
leading strand will be one which will be synthesis in the direction of the opening of replication fork while synthesising in the opposite diretion will be lagging strand.
A will be leading strand
B will be lagging strand
Cwill be lagging strand
D will be leading strand
ligase is needed by the lagging strand because okazaki fragments are formed.so if ligase inhibitor is given than it will not be able to ligate the lagging strands.