Blood Banking Question: 1.Polyspecific anti-human globulin reagents must contain

Question

Blood Banking Question:

1.Polyspecific anti-human globulin reagents must contain adequate levels of which of the following?

2. Mix and Match the correct product for each patient situation:

Select the most appropriate product for each patient:

a) Classic hemophiliac with bleeding into joints with a 12.0 g/dL Hemoglobin

      [ Choose ]            Red Blood Cells            Cryopreciptiated AHF            Platelets            Fresh Frozen Plasma      

b) 4 year old with subacute lymphocytic leukemia and much bruising and a 11.0 g/dL Hemoglobin

      [ Choose ]            Red Blood Cells            Cryopreciptiated AHF            Platelets            Fresh Frozen Plasma      

c) 68 year old with heart failure and anoxia secondary to iron deficiency anemia

      [ Choose ]            Red Blood Cells            Cryopreciptiated AHF            Platelets            Fresh Frozen Plasma      

d) Factor V deficient patient that is pregnant and scheduled for C-section the next day

Explanation / Answer

1. Polyspecifc anti human globulin contain IgG antibodies and antibodies reactive with human reactive complement components of C3b & C3d. These abto complement antobodies are IgM class monoclonals and they impart the necessary sensitivity to the reagent. Each batch of reagents undergoes rigorous quality control at various stages of manufacture for its specificity, avidity & titre.

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