Imagine that you are part of a research team that specializes in diagnosing diso
ID: 88688 • Letter: I
Question
Imagine that you are part of a research team that specializes in diagnosing disorders associated with malfunctioning cellular organelles and structures. Medical doctors consult your group to help diagnose particularly difficult cases.
-Patient History:
-Seven year-old male
-Fatigue
-Muscle weakness
-Low endurance
-Loss of coordination
-Progressive difficulty walking
-Physical Examination
-Muscle loss & deformity
-Awkward gait
-Difficulty breathing
-Laboratory Results
-Cells have abnormal shape
-Cell division is abnormal
-Impaired intracellular movement of materials
Diagnosis:
Malfunctioning Organelle: ___________________________
Rationale for Diagnosis (explanation of how history, physical examination and laboratory results suggest diagnosis ):
Explanation / Answer
Diagnosis:
Malfunctioning Organelle Is Cytoskeleton.
The cytoskeleton of a cell helps provide shape, strength, and an organized structure to the cell. The cytoskeleton can be compared to a transport network facilitating various types of movement in the cell. It helps with cell reproduction, the movement of organelles, the functions of muscles and intracellular transport between the organelles. It also enables the separation of daughter chromosomes to opposite poles during cell division.
Cytoskeleton Malfunction
Malfunctions in the cytoskeleton are linked to some diseases. It affect synaptic signals and organelle or vesicle trafficking. For example, in synaptic cytoskeletons, the diseases tend to be inherited. These include mental retardation, spastic paraplegias and spinocerebellar ataxias. The conditions like Muscle loss, deformity and breathing difficulty are also few characteristics of cytoskeleton Malfunction.