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In the Cori cycle, when glucose is degraded by glycolysis to lactate in muscle,

ID: 924655 • Letter: I

Question

In the Cori cycle, when glucose is degraded by glycolysis to lactate in muscle, the lactate is excreted into the blood and returns to the liver where it is converted back into glucose by gluconeogenesis. Sort the following list of enzymes into those that are involved in •both glycolysis (including lactate formation) and gluconeogenesis, •glycolysis of glucose to lactate only, •gluconeogenesis only, or •neither pathway.

In the Cori cycle, when glucose is degraded by glycolysis to lactate in muscle, the lactate is excreted into he blnd returns to the liver where it is converted back into glucose by gluconeogenesis. Sort the following list of enzymes into those that are involved in both glycolysis (including lactate formation) and gluconeogenesis, .glycolysis of glucose to lactate only, .gluconeogenesis only, or neither pathway obotw ny colysis rincuaing lactate foraation) and @lucoeogenesis Enzymes involved only in gluconeogenesis from lactate Enzymes involved in neither glycolysis nor gluconeogenesis Enzymes involved in both Enzymes involved only in glycolysis and gluconeogenesis glycolysis of glucose to lactate pyruvate kinasefructose phosphoenolpyruvate lhol e kinase 1,6-bispho pyruvate 1,6-bisphosphatasecarboxykinase dehydrogenase decarboxylase glyceraldehyde 3-phosphate hexokinase lactate dehydrogenase dehydrogenase

Explanation / Answer

Enzymes involved in both glycolysis and glucogenesis

phosphoenolpyruvate carboxykinase

Enzymes involved in glycoslysis of glucose to lactate

pyruvate kinase

hexokinase

Enzymes involved only in glucogenesis from lactate

pyruvate carboxylase

fructose 1,6-bisphosphatase

Enzymes involved in neither glycolysis nor glucogenesis

alcohol dehydrogenase

glyceraldehyde 3-phosphate

lactate dehydrogenase