AP Biology 10, added to or deleted from the DN group is tions where at least one
ID: 93344 • Letter: A
Question
AP Biology 10, added to or deleted from the DN group is tions where at least one base is either as it copied during ONA teplication Let s investigne the effects of these is a. Here is your onginal ONA sequenea trom thislab and amino acid sequenee that as translated from MET THR AR b, Lens simulate a trameshin mutation by adding an addiuonal base between the 30. ar bases. The base A was accidentally added to the sequence of the gene. Now wansoitoo uwo new DNA stand into mBHA, and then also ranulate it e. Did this change in the DNA sequence cause any significant change to the protein produced? Explain. d. Why are insertions and deletions called Trameshim mutations, and what is meant by the "reading frame' ola gene? 9 of 11 Developed by Kim B. Foglia www. Explore Biology.com 02008Explanation / Answer
c. Yes, this change in the DNA sequence causes significant change to the produced protein because of the change in aminoacid sequence.
d. Insertions and deletions are caled frameshift mutations because they are caused by insertions or deletions of a number of nucleotides in DNA sequence which cannot be divided by 3 and also due to change in aminoacid sequence.
Reading frame of a gene is nothing but the way of divding the nucleotides sequence in either DNA or RNA molecule into set of successive and non overlapping triple molecules.