If your hypothesis that a gene in humans acts as a positive regulator in respons

Question

If your hypothesis that a gene in humans acts as a positive regulator in response to a peptide hormone is correct, what phenotype will you expect in a knockout mouse for that orthologous gene in mouse? A. The knockout mouse will increase the response to the hormone. B. The knockout mouse will decrease the response to the hormone. C. The knockout mouse will still have the normal response to the hormone. D. None of the above If your hypothesis that a gene in humans acts as a positive regulator in response to a peptide hormone is correct, what phenotype will you expect in a knockout mouse for that orthologous gene in mouse? A. The knockout mouse will increase the response to the hormone. B. The knockout mouse will decrease the response to the hormone. C. The knockout mouse will still have the normal response to the hormone. D. None of the above A. The knockout mouse will increase the response to the hormone. B. The knockout mouse will decrease the response to the hormone. C. The knockout mouse will still have the normal response to the hormone. D. None of the above

Explanation / Answer

Answer:

A. The knockout mouse will increase the response to the hormone.

Genes in the Mouse and Man are similar in function, due to this reason, these two different species are considered as orthologus genes after evolution.

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