The diagram below shows a rod photoreceptor cell, a bipolar cell, and a retinal

Question

The diagram below shows a rod photoreceptor cell, a bipolar cell, and a retinal ganglion cell (RGC). The synapse between the rod and the bipolar cell is inhibitory. The synapse between the bipolar cell and the RGC is excitatory. AP-7 is a drug that specifically activates metabotropic glutamate receptors. Applying AP-7 to the bipolar cell above:

a. would have no effect

b. would make it respond as if it were in constant darkness

c. would make it respond as if it were in constant light

Explanation / Answer

The mGLURs receptors functions to help in synaptic transmission and neuronal excitability throughout the central nervous system. It  binds glutamate within a large extracellular domain and transmits signals through the receptor cell protein to intracellular signaling partners.

Now for the receptor cell diagram above

In the bipolar cell ,it wuld have no effect , as rod cell functions in less intense light , not constant dark and constant light .

So, answer is a.

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