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Pick the right answer: 1) Hexokinase: a. Promotes the retention of glucose in th

ID: 1036446 • Letter: P

Question

Pick the right answer:

1) Hexokinase:

a. Promotes the retention of glucose in the cell

b. Is irreversible

c. Undergoes a dramatic conformational change upon binding substrate

d. A and B

e. All of the above

2) Which product of triose phosphate isomerase is favored thermodynamically?

a. Triose 3 phosphate

b. Triose 1 phosphate

c. Dihydroxyacetone phosphate

d. Glyceraldehyde 3-phosphate

e. 3-phosphoglycerate

3) The formation of 1, 3-bisphosphoglycerate:

a. Involves the production of NADH

b. Produces CO2

c. Is highly energetic and irreversible

d. A and C

e. All of the above

4) The formation of phosphoenolpyruvate during glycolysis requires:

a. A dehydration reaction

b. The reduction of NADH

c. The cleavage of ATP

d. Substrate level phosphorylation

e. Phosphorylation of pyruvate

5) Lactate is:

a. Produced with the NADH formed during glycolysis

b. Generally metabolized in the liver

c. Able to block glycolysis if not removed from the muscle cell

d. A and C

e. All of the above

Explanation / Answer

1) Hexokinase is the enzyme used in the first step of glycolysis .

In this glucose gets phosphorylated at 6th position and therefore there occurs the retention of conformation . Also it is irreversible

Hence the ans. D

2)ans is D . In this Glyceraldehyde 3 phosphate is the favoured product.

3)ans is A . Formation of 1,3 bpg involves the formation of NADH .

4)water is removed during the formation of phosphoenolpyruvate pyruvate therefore option a.

5) lactate production leads to the production of NAD+ .

And it is metabolised in the muscles.

Ans should be C I.e it is able to block glycolysis if not removed from the muscle cell.