Study Guide Reduction and hydrolysis of nitrile Preparation of aldehyde from nit

Question

Study Guide Reduction and hydrolysis of nitrile Preparation of aldehyde from nitrile Preparation of acid chloride Recognize enol_form and be able to draw it when a ketone or aldehyde is given Haloform reaction; pka of alpha-hydragens Enolate alkylation; hydrolysis and decarboxylation (loss of CO_2) of ester Acetoacetic and malonic ester synthesis IUPAC of nitrile and amide Reactivity of carboxylic acid derivatives Methods for preparing esters Beta-ketoacids Michael reaction, including donors and acceptors

Explanation / Answer

(1) Nitriles on reduction gives primary amine

RCN + 4 (H) -----------------> RCH2NH2

Nitriles on hydrolysis gives carboxylic acid.

RCN + 2 H2O --------------> RCOOH + NH3

(2) Nitriles react with DIBAL-H followed by hydrolysis give aldehydes.

RCN -----------DIBAL-H----> RCHO

(3) CH3CHO <-----------> CH2=CHOH

acetaldehyde                   enol form

(4) Aldehydes and ketones having CH3CO - group reacts with halogen in the presence of a base to form haloform.

CH3CHO + I2 ---------NaOH-------------> CHI3 + HCOONa

Related Questions

Navigate

• Browse (All)
• Browse S
• Subjects

---