Please fill in the blanks and provide a short answer of why you chose your answe
ID: 11287 • Letter: P
Question
Please fill in the blanks and provide a short answer of why you chose your answer.12. An in vitro assembly reaction for microtubules or microfilaments consists of an energetically unfavorable step referred to as _____________________. This step involves the formation of small
__________________________ that promote further assembly.
13. The assembly subunit for microtubules is a dimer of ___________________, preferably associated with
( ATP / ADP / GTP / GDP ). The assembly subunit for microfilaments is a monomer of
______________________, preferably associated with ( ATP / ADP / GTP / GDP ).
14. The role of nucleotide hydrolysis in the assembly dynamics of microtubules and microfilaments is fundamentally to promote rapid __________________________________.
Explanation / Answer
12. An in vitro assembly reaction for microtubules or microfilaments consists of an energetically unfavorable step referred to as NUCLEATION _. This step involves the formation of small
GAG FRAGMENTS that promote further assembly.
13. The assembly subunit for microtubules is a dimer of TUBULIN preferably associated with
( ATP / ADP / GTP / GDP ). The assembly subunit for microfilaments is a monomer of
ACTIN , preferably associated with ( ATP / ADP / GTP / GDP ).
14. The role of nucleotide hydrolysis in the assembly dynamics of microtubules and microfilaments is fundamentally to promote rapid ENERGY AND POLYMERISATION