In general, why might cell-wall inhibiting antimicrobial drugs be less effective
ID: 134754 • Letter: I
Question
In general, why might cell-wall inhibiting antimicrobial drugs be less effective on gram-negative bacteria compared to gram-positive bacteria?
Select one:
a. The peptidoglycan found in gram-positive bacteria is structurally different from that in gram-negative bacteria.
b. The gram-negative bacteria do not synthesize peptidoglycan.
c. The gram-negative bacteria digest these drugs at a much higher rate than gram-positive bacteria.
d. The outer membrane of the gram-negative bacteria inhibits penetration of the drug.
e. The mutation rate of gram-negative bacteria is much greater than that of gram-positive bacteria.
Explanation / Answer
d. d. The outer membrane of the gram-negative bacteria inhibits penetration of the drug.
The gram negative bacteria possesses an outer membrane structure, which prevents the penentration of antimicrobial drugs