Please help with the following based off this fantastic packet. Thank you so muc
ID: 141936 • Letter: P
Question
Please help with the following based off this fantastic packet. Thank you so much and god bless your day <3- create 1-2 more entries into your annotated bibliography.
-annotate a bibliography 7 sources minimum Complement and Bacterial Infections: From Molecular Mechanisms to Therapeutic Applications Dani A.C. Heesterbeekhieu L.Angelier Richard A. Harrisonb Suzan H.M. Rooijakkers Department of Medical Microbiology, Utrecht University Medical Center, Utrecht, The Netherlands Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK Keywords Complement Bacteria Infections Antibody therapy Antibiotic resistance Inflammatory diseases Eculizumab how such inhibitors may increase the risk of bacterial infec- Neisseria Membrane attack complex to prevent unwanted complement activation in autoim- mune inflammatory diseases. A better understanding of tions is essential if such therapies are to be successful. 2018 5 Karger AG, Basel Abstract Complement is a complex protein network of plasma, and Complement in Innate Immune Defenses Against an integral part of the innate immune system. Complement Bacteria activation results in the rapid clearance of bacteria by im- mune cells, and direct bacterial killing via large pore-form- The human body is constantly exposed to bacteria that ing complexes. Here we review important recent discover- may be present in the environment, shed by other indi- ies in the complement field, focusing on interactions rele viduals, or living in symbiosis with the host. Normally vant for the defense against bacteria. Understanding the physical barriers (skin or epithelial cell layers) success- molecular interplay between complement and bacteria is of fully protect the body from bacterial infections. However great importance for future therapies for infectious and in when bacteria cross these barriers and invade the human flammatory diseases.Antibodies that support complement-body, the innate immune system provides the first line of dependent bacterial killing are of interest for the develop- response, capable of clearing bacteria within minutes to ment of alternative therapies to treat infections with antibi hours upon infection [1].Complement isessential for this otic-resistant bacteria. Furthermore, a variety of novel p eimination of invading bacteria. Complement pro- therapeutic complement inhibitors have been developed teins are present in the blood and body fluids as inactive KARGER 20185. Karger AG Basel Prol Suzan H... Roojakkers Department of Medical Microbiology. Utrecht Univeity Medical Cemter NL-1584 CX Utrecht (The Netherlands
Explanation / Answer
Bibliography related to the given aricle is given below.
Holers.
Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.
Mold C.
Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine
National Institutes of Health, Bethesda, Maryland, U.S.A
Ignatov SG, Dragunova SF, Perelygin VV, Vorob'ev AA.
Nydegger .
Central Laboratory of Haematology, University of Bern, Switzerland.